Indian Journal of Public Health Research & Development

P. Jayashri ¹, Joseph John ², I. Meignana Arumugham ³, R. Pradeep Kumar ³, D. Srisakthi ⁴

Affiliations
1 Senior Lecturer, Department of Public Health Dentistry, Saveetha Dental College, SIMATS, Chennai, Tamil Nadu, IN
2 Former Professor, Department of Public Health Dentistry, Saveetha Dental College, SIMATS, Chennai, Tamil Nadu, IN
3 Professor, Department of Public Health Dentistry, Saveetha Dental College, SIMATS, Chennai, Tamil Nadu, IN
4 Reader, Department of Public Health Dentistry, Saveetha Dental College, SIMATS, Chennai, Tamil Nadu, IN

Abstract

Background: Malocclusion has a negative impact on the oral health-related quality of life and has all been associated with an unacceptable dental appearance. Dental caries is a common complication of malocclusion. Epidemiological data on malocclusion and dental caries is of interest for dental public health programs, clinical treatment, screening for treatment priority and resource planning. Therefore the objective of the present study is to determine the prevalence of malocclusion and its relationship with dental caries among 12 to 15 year Old School Children of Chandigarh, India.

Method: The present study was conducted among 1368 school going children of Chandigarh in the age group of 12 to 15 years. The subjects were selected from four randomly selected schools of Chandigarh. Dentition status was assessed using the DMFT index by Klein, Palmer, Knutson, and Malocclusion were quantified based on the presence or absence of dentofacial anomalies which was recorded in a structured format.

Results: Prevalence of malocclusion and dental caries in the present study was found to be 28.9% and 31.4%. A significant negative correlation was observed between Malocclusion and Dental caries among subjects having Normal occlusion and Malocclusion.

Conclusion: Prevalence of malocclusion and dental caries was greater among older than younger children Results from the present study revealed that Normal occlusion and malocclusion had no or weak significant effect on overall dental caries.

Keywords

Dental Caries, Malocclusion, School Children.

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C. Cinthura ¹, Lakshmi Thangavelu ², S. Rajeshkumar ², Deepa Gurunadhan ³, R. Pradeep Kumar ⁴, Anitha Roy ²

Affiliations
1 Undergraduate Student, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, IN
2 Associate Professor, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, IN
3 Professor, Department of Pedodontics & Preventive Dentistry, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, IN
4 Professor, Department of Public Health Dentistry, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, IN

Abstract

Aim: To analyse the COX2 inhibitory activity of Abutilon indicum.

Objective: The main objective of this study is to analyse the COX2 inhibitory activity of Abutilon indicum.

Background: Prostaglandins are important mediators of the body’s response to pain and inflammation, and are formed from essential fatty acids found in cell membranes. This reaction is catalysed by cyclooxygenase, a membrane associated enzyme in two isoforms - COX-1 and COX-2. Abutilon indicum ,commonly known as the Indian mallow is well known for its therapeutic values and further study of its COX-2 inhibitory activity is beneficial.

Conclusion: Medicinal plants and shrubs which have little or no side effects have to be further investigated. Further study on its COX-2 inhibition will increase its therapeutic value also as an anti-inflammatory with added benefits

Keywords

Ethnomedicinal, Anti-Arthritic, COX2 Inhibition, Medicinal Uses, Prostaglandin.

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Gayathri Karthikeyan ¹, T. Lakshmi ², S. Rajeshkumar ², Anitha Roy ², Deepa Gurunadhan ³, R. V. Geetha ⁴, R. Pradeep Kumar ⁵

Affiliations
1 Undergraduate Student, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, IN
2 Associate Professor, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, IN
3 Professor, Department of Pedodontics & Preventive Dentistry, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, IN
4 Associate Professor, Department of Microbiology, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu,, IN
5 Professor, Department of Public Health Dentistry, Saveetha Dental College, SIMATS, Saveetha University Chennai, Tamilnadu, IN

Abstract

Introduction: Ficus racemosa is widely used in ayurvedic medicine in India, mostly as fruits and bark decoction to treat uncontrolled diabetes, the objective of this study is to study the uptake of glucose in L6 myotubes by Ficus racemosa.

Background: Diabetes is a common metabolic disease characterized by abnormally high plasma glucose levels, leasing to major complications, such as diabetic neuropathy, retinopathy and cardiovascular disease. Presently available oral hypoglycaemic agents exhibit several side effects. Therefore, there is a need for more effective oral antihyperglycemic agent, particularly those that normalize both insulin and glucose levels.

Method: Cell culture: L6, a mono layer myoblast culture (obtained from NCCS, Pune-Passageno-19) was cultured in the DMEM. In vitro glucose uptake activity: Glucose uptake assay was followed by the methodology of (Gupta et al).

Result: It was observed from the results that Ficus racemosa extract at different concentrations exhibited substantial degree of glucose uptake in skeletal muscle cells, which was compared with that of Standard Metformin. A maximum glucose uptake of 53% was observed for ficus 30mg/ml, whereas metformin exhibited 61% of glucose uptake. The IC50 of ficus extract and metformin was found to be 2.57mg/ml and 1.79mg/ml respectively.

Conclusion: From the study that was conducted above it can be concluded that Ficus racemosa had a better glucose uptake compared to the with that of Standard Metformin used by diabetic patients.

Keywords

Ficus racemose, Glucose, l6 Motube, Uptake, Myoblast.

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T. Sai Sandhya ¹, T. Lakshmi ², S. Rajeshkumar ², Anitha Roy ², Deepa Gurunathan ³, R. V. Geetha ⁴, R. Pradeep Kumar ⁵

Affiliations
1 Undergraduate Student, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University, Chennai, Tamilnadu, IN
2 Associate Professor, Department of Pharmacology, Saveetha Dental College, SIMATS, Saveetha University, Chennai, Tamilnadu, IN
3 Professor, Department of Pedodontics & Preventive Dentistry, Saveetha Dental College, SIMATS, Saveetha University, Chennai, Tamilnadu, IN
4 Associate Professor, Department of Microbiology, Saveetha Dental College, SIMATS, Saveetha University, Chennai, Tamilnadu, IN
5 Professor, Department of Public Health Dentistry, Saveetha Dental College, SIMATS, Saveetha University, Chennai, Tamilnadu, IN

Abstract

Introduction: Drug abuse is an extreme desire to obtain and use increasing amounts of one or more substances. Drug abuse indicates the following risk factors for developing drug abuse problems include poor relationships with parents, inadequate supervision over adolescent activities, poor achievement in schools and so on.

Materials & Method: An online survey comprising 17 questions was administered to the participants of age group 14-19.The results are statistically analysed.

Results and Discussion: From the survey conducted, it is analysed that 67%of the adolescents have attended many drug awareness programmes. 45% of them say that alcoholism and drug addiction are genetically inherited.

Conclusion: The abuse of alcohol and drugs has resulted in significant morbidity and mortality among adolescents worldwide.School-based health centers should have the capacity to counsel students who are in need of such treatment plans and connect students to available community resources.

Keywords

Drug Abuse, Poor Relationship, Marijuana, Health Centre, Community.

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